INBDE (Integrated National Board Dental Examination) Practice Exam

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Which condition involves problems at the motor end plate?

  1. Multiple Sclerosis

  2. Myasthenia Gravis

  3. Amyotrophic Lateral Sclerosis

  4. Parkinson's Disease

The correct answer is: Myasthenia Gravis

Myasthenia Gravis involves problems at the motor end plate. In Myasthenia Gravis, there is a disruption at the neuromuscular junction where the motor end plate is located. This disruption leads to weakness and fatigue of skeletal muscles due to the inadequate transmission of nerve signals to the muscles. Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Parkinson's Disease are neurological conditions that affect different aspects of the nervous system but do not predominantly involve problems at the motor end plate like Myasthenia Gravis does. Multiple Sclerosis affects the central nervous system, Amyotrophic Lateral Sclerosis affects the motor neurons in the spinal cord and brain, and Parkinson's Disease affects the dopaminergic neurons in the brain.