INBDE (Integrated National Board Dental Examination) Practice Exam

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Multiple Sclerosis affects which of the following cells?

  1. Neurons

  2. Astrocytes

  3. Oligodendrocytes

  4. Microglia

The correct answer is: Oligodendrocytes

Multiple Sclerosis (MS) is a disease that affects the central nervous system (CNS) by damaging the myelin sheath, which is the protective covering of nerve fibers. Oligodendrocytes are the cells responsible for producing and maintaining the myelin sheath in the CNS. In MS, the body's immune system mistakenly attacks and damages the myelin, leading to a disruption in nerve signaling. - Neurons are the functional cells responsible for transmitting nerve impulses and are not typically directly affected by MS. - Astrocytes are support cells in the CNS and may be involved in the response to CNS injury, but they are not the primary target cell in MS. - Microglia are immune cells in the CNS involved in inflammation and response to injury, but they are not the primary cells affected in MS.