INBDE (Integrated National Board Dental Examination) Practice Exam

Which syndrome is characterized by mucosal atrophy, dysphagia, iron deficiency anemia, and increased risk of oral cancer?

1. MEN 2B

2. Scleroderma

3. Plummer Vinson Syndrome

4. Behcet's

The correct answer is: Plummer Vinson Syndrome

Plummer-Vinson syndrome, also known as Paterson-Brown-Kelly syndrome, is a rare disease that is characterized by difficulty swallowing (dysphagia), iron deficiency anemia and mucosal atrophy of the oral cavity. This syndrome can also increase the risk of developing oral cancer. Other syndromes may also present with some of these symptoms, but Plummer-Vinson syndrome is the only one that includes all of them. MEN 2B usually presents with multiple endocrine tumors and may cause dysphagia, but it is not associated with mucosal atrophy or increased risk of oral cancer. Scleroderma often involves thickening and hardening of the skin and tissues, but it is not associated with dysphagia or iron deficiency anemia. Behcet's syndrome may cause ulcers and inflammation in various parts of the body, but it is not typically associated with mucosal atrophy, dysphagia, or iron deficiency anemia. Therefore, C is the most accurate and relevant answer.