INBDE (Integrated National Board Dental Examination) Practice Exam

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What leads to the formation of a cleft primary palate?

Non-fusion of the intermaxillary segment with palatine shelves
Non-fusion of medial nasal prominences
Non-fusion of maxillary prominences
Non-fusion of palatine shelves with each other

The correct answer is: Non-fusion of the intermaxillary segment with palatine shelves

The formation of a cleft primary palate is primarily attributed to the non-fusion of the intermaxillary segment with the palatine shelves. During normal development, these structures should fuse together to form the primary palate. If this fusion does not occur properly, a cleft primary palate can result. Option B, non-fusion of medial nasal prominences, is involved in the formation of the secondary palate, not the primary palate. Option C, non-fusion of maxillary prominences, is also related to the secondary palate development. Option D, non-fusion of palatine shelves with each other, would lead to a cleft secondary palate, not a cleft primary palate.