INBDE (Integrated National Board Dental Examination) Practice Exam

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What does MEN 2B syndrome include?

  1. Multiple neuromas, Medullary thyroid cancer, Pheochromocytoma of the adrenal gland

  2. Gingival hyperplasia, Strawberry gingivitis, Hardening of skin

  3. Mucosal atrophy, Dysphagia, Iron deficiency anemia

  4. Autoantibodies against basement membrane, Autoantibodies against desmosomes

The correct answer is: Multiple neuromas, Medullary thyroid cancer, Pheochromocytoma of the adrenal gland

MEN 2B syndrome, also known as multiple endocrine neoplasia type 2B, is a rare genetic disorder characterized by the presence of tumors in various endocrine glands, including neuromas (benign nerve tumors), medullary thyroid cancer, and pheochromocytoma (tumors of the adrenal gland). The options B, C, and D all describe symptoms or conditions that are not associated with MEN 2B syndrome. For example, gingival hyperplasia and strawberry gingivitis are both conditions related to the gums, which are not affected by MEN 2B syndrome. Mucosal atrophy and dysphagia are symptoms related to the digestive system, which is also not affected by MEN 2B syndrome. Autoantibodies against basement membrane and desmosomes are related to autoimmune disorders, which are not associated with MEN 2B syndrome. Therefore, A is the most accurate and fitting description of MEN 2B syndrome.