INBDE (Integrated National Board Dental Examination) Practice Exam

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What disease involves autoantibodies against the basement membrane, subasilar location?

  1. Pemphigoid

  2. Pemphigus

  3. Wegener's Granulomatosis

  4. Plummer Vinson syndrome

The correct answer is: Pemphigoid

Pemphigoid is the correct answer because it is the only option that involves autoantibodies targeting the basement membrane, specifically in a subepidermal location. Pemphigus is incorrect because it involves autoantibodies targeting desmoglein, a protein involved in cell adhesion. Wegener's Granulomatosis is incorrect because it is a form of vasculitis and does not involve autoantibodies. Plummer Vinson syndrome is incorrect because it is a condition characterized by iron deficiency anemia and esophageal webbing, not related to autoantibodies.

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