INBDE (Integrated National Board Dental Examination) Practice Exam

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Syndrome with cleft lips + pits

  1. Down syndrome

  2. Van der Woude syndrome

  3. Crouzon syndrome

  4. Apert syndrome

The correct answer is: Van der Woude syndrome

Syndrome with cleft lips and pits is a characteristic of Van der Woude syndrome, which is caused by a genetic mutation that affects facial development. While Down syndrome is also associated with some congenital abnormalities, cleft lips and pits are not typically seen in individuals with Down syndrome. Similarly, Crouzon syndrome and Apert syndrome both affect facial development, but do not specifically include cleft lips and pits as a symptom. Therefore, B is the most appropriate choice for this question.