INBDE (Integrated National Board Dental Examination) Practice Exam

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Intranuclear inclusions are found in which two conditions?

  1. Influenza and Mononucleosis

  2. Herpes Simplex and Oral Hairy Leukoplakia

  3. Chickenpox and Shingles

  4. Measles and Rubella

The correct answer is: Herpes Simplex and Oral Hairy Leukoplakia

Intranuclear inclusions are characteristic features seen in both Herpes Simplex and Oral Hairy Leukoplakia. In Herpes Simplex infection, intranuclear inclusions, known as Cowdry Type A inclusions, are observed in affected cells. These inclusions are formed by the virus replicating within the nucleus of the cell. In Oral Hairy Leukoplakia, caused by the Epstein-Barr virus (EBV), intranuclear inclusions known as 'Owl's eye inclusion bodies' can be seen in the epithelial cells of the oral mucosa. Therefore, option B is correct as intranuclear inclusions are associated with both Herpes Simplex and Oral Hairy Leukoplakia. In the context of the other options: A. Influenza and Mononucleosis do not typically present with intranuclear inclusions. C. Chickenpox and Shingles are caused by varicella-zoster virus and typically do not exhibit intranuclear inclusions. D. Measles and Rubella do not commonly display intranuclear inclusions in affected cells.

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