INBDE (Integrated National Board Dental Examination) Practice Exam

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Heck's disease is caused by what HPV strains?

  1. 6 and 11

  2. 16 and 18

  3. 13 and 32

  4. 31 and 45

The correct answer is: 13 and 32

Heck's disease, also known as Focal Epithelial Hyperplasia (FEH), is caused by HPV strains 13 and 32. This benign viral infection typically presents as multiple soft, pink, or white papules in the oral mucosa, particularly in the buccal and labial mucosa. HPV strains 6 and 11 are commonly associated with oral condylomas (warts), while strains 16 and 18 are known for their association with high-risk genital cancers. Strains 31 and 45 are also high-risk HPV types associated with cervical cancer development.