INBDE (Integrated National Board Dental Examination) Practice Exam

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Hashimoto's thyroiditis typically starts out as __________, then becomes __________.

  1. Hyper then hypo

  2. Hypo then hyper

  3. Euthyroid then hypo

  4. Hypo then euthyroid

The correct answer is: Hyper then hypo

Hashimoto's thyroiditis is an autoimmune condition that leads to inflammation of the thyroid gland, resulting in an underactive thyroid (hypothyroidism). Initially, as the immune system attacks the thyroid gland, there can be a phase of increased thyroid hormone release causing hyperthyroidism. This is known as the thyrotoxic phase. However, over time, as the thyroid gland becomes more damaged and unable to produce enough thyroid hormone, hypothyroidism develops. Therefore, Hashimoto's thyroiditis typically starts out as hyper (hyperthyroidism) and then progresses to hypo (hypothyroidism).

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