INBDE (Integrated National Board Dental Examination) Practice Exam

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At what stage of tooth development does tetracycline damage occur?

Calcification
Eruption
Initiation
Morphogenesis

The correct answer is: Calcification

Tetracycline damage occurs during the stage of calcification in tooth development. Tetracycline is known to bind to calcium ions and become incorporated into the developing teeth, leading to discoloration or staining of the teeth. This incorporation typically happens during the calcification stage when mineralization of the tooth structure is taking place. The other stages of tooth development—initiation, morphogenesis, and eruption—do not involve the mineralization process where tetracycline can have a damaging effect.