INBDE (Integrated National Board Dental Examination) Practice Exam

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Amides are biotransformed by

  1. Kidneys

  2. Liver

  3. Plasma

  4. Lungs

The correct answer is: Liver

Amides are commonly metabolized in the liver through a process known as hydrolysis. This metabolic pathway involves the breaking down of the amide bond within the molecule. The liver is a key organ for drug metabolism and plays a crucial role in transforming various compounds, including amides, into their respective metabolites that can be eliminated from the body. In contrast, the kidneys, plasma, and lungs are not primarily responsible for the biotransformation of amides.

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